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BST-2 and HIV-1 Gag colocalize along the cell surface and in endosomes. Cells (HeLa), which express BST-2 constitutively, were transfected to express an HIV-1 genome lacking the vpu gene, as well as GFP (green in the color image) as a marker of the transfected cells, then stained for the structural HIV-1 protein Gag (p17/p55; left panel; blue in the color image) and BST-2 (middle panel; red in the color image). In the color (merge) image, the overlap of Gag and BST-2 appears purple.
