Mutations in EVR do not restore abscission in ida or hae hsl2 mutant flowers. (A-D) Organ separation is blocked in ida (C) and hae hsl2 (A) mutant flowers (stage 17), and is not rescued in ida evr (D) or hae hsl2 evr (B) flowers (stage 17). (E) Alternative pathways for the relationships between NEV, EVR, IDA and HAE/HSL2. In both, EVR is predicted to act as a negative regulator of abscission and to function downstream of NEV. In the simplest model, NEV and EVR act upstream of both IDA and HAE/HSL2. Alternatively, NEV and EVR could function in a converging pathway, in which EVR acts upon HAE/HSL2, or further downstream.