. Author manuscript; available in PMC: 2010 Apr 23.

Published in final edited form as: Toxicol Appl Pharmacol. 2008 Dec 9;235(2):143–152. doi: 10.1016/j.taap.2008.11.017

Table 6.

MMTP [3-methyl-4-(methylthio)-phenol] formation from fenthion and TEPP (tetraethylpyrophosphate) inhibition in microsomal fractions isolated from liver, gills and olfactory tissues in freshwater-acclimated rainbow trout (Oncorhynchus mykiss)

Tissue	Inhibitor	MMTP Formation
Tissue	Inhibitor	NADPH-independent	NADPH-dependent
Liver	Control	7.5±3.2^a	145.9±4.4^a
	100 μM TEPP	bdl^b	138.4±10.3^a
	500 μM TEPP	bdl^b	65.4±11.1^b
	1000 μM TEPP	bdl^b	bdl^c
Gills	Control	133.5±5.8^a	117.5±9.5^a
	100 μM TEPP	bdl^b	105.3±8.9^a
	500 μM TEPP	bdl^b	74.3±10.1^b
	1000 μM TEPP	bdl^b	bdl^c
Olfactory tissue	Control	71.2±11.1^a	240.2±28.0^a
	100 μM TEPP	bdl^b	254.3±18.1^a
	500 μM TEPP	bdl^b	100.2±13.3^b
	1000 μM TEPP	bdl^b	bdl^c

Data are presented as pmol/min/mg protein and as mean±SD in pmol/min/mg protein (n=3–5 individuals with 3 replicates for each one (liver and gill); 2 replicates for each one of the 3 pooled samples (olfactory tissue)). Different letters mean significant differences between groups and its own control (P<0.01; One-way ANOVA, Tukey’s test).

bdl: below detection limit (<0.3 pmol/min/mg protein).