Figure 3.

¹H CSI grid plots, ¹H 1D summation spectra, and t-cho spectroscopic images of the CWR22 tumor region. A), D) & G). 0 hour. B), E) & H) 4 hour. C), F) & I) 48 hour. Figures A, B, C are CSI grid plots overlaid on tumor T2-weighted images; Figures D, E, F are the spectra calculated from summing the spectra from all the tumor voxels; Figures G, H, I are spectroscopic images of tumor t-cho intensities in the tumor. Water suppressed slice selective CSI images were acquired with FOV 32 × 32 mm², 16 × 16 phase encoding steps, slice thickness 4 mm, TR 1s, TE 75 ms, spectral width 2000 Hz, NEX 8. Only the CSI grid covering the tumor region is shown by overlaying on top of the corresponding slice of the anatomical T2-weighted tumor image. T-cho spectroscopic images were generated in a 16 × 16 grid using measured t-cho peak areas in arbitrary units with a full FOV of 32 mm and the final displays were smoothed with cubic interpolation to 256×256 pixels with the same image intensity scale.