Table 2. Odds ratio and 95% confidence intervals for cognitive impairment (MMSE <24) at follow-up by adiposity measures in older persons with type 2 diabetes (n = 221).
Unadjusted | Model 1 | Model 2 | |||||||
OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | P | |
BMI (kg/m2) | 0.13 | 0.76–1.01 | 0.13 | 0.29 | 0.75–1.10 | 0.29 | 0.36 | 0.77–1.10 | 0.360 |
WHR * | 1.42 | 1.34–3.11 | 0.04 | 1.11 | 1.01–1.12 | 0.04 | 1.13 | 1.15–2.08 | 0.050 |
WC * (cm) | 1.81 | 1.21–3.51 | 0.03 | 1.33 | 1.21–2.89 | 0.04 | 1.23 | 1.09–1.41 | 0.008 |
Total fat mass (kg) | |||||||||
Tertile 1 | 1.00 | - | - | 1.00 | - | - | 1.00 | - | - |
Tertile 2 | 1.41 | 0.70–2.78 | 0.47 | 1.26 | 0.65–2.41 | 0.46 | 1.17 | 0.54–2.39 | 0.64 |
Tertile 3 | 2.20 | 1.23–4.32 | 0.02 | 1.92 | 1.2–3.71 | 0.04 | 1.68 | 1.08–3.52 | 0.02 |
Model 1 included the following confounders: age, gender, yrs of education, physical activity, depression.
Model 2 = Model 1 + BMI, hypertension, smoking IMT, Hb1Ac, CV-PPG, IL-6, Drug vs. diet §
see methods.
*WHR and WC were entered separately in models.