Table 2.
Event rates and hazard ratios for lung cancer mortality by cardiorespiratory fitness (CRF) groups, Aerobics Center Longitudinal Study, Dallas, Texas, 1974–2003
| Deaths for lung caner | Event rate* | HR† | 95% CI† | HR‡ | 95% CI‡ | |
|---|---|---|---|---|---|---|
| All men (n=38,000) | ||||||
| Low CRF | 86 | 7.3 | 1.00 | Referent | ||
| Moderate CRF | 86 | 3.1 | 0.48 | 0.35, 0.67 | ||
| High CRF | 60 | 2.3 | 0.43 | 0.28, 0.65 | ||
| P linear trend | <0.001 | <0.001 | ||||
| Never smoker (n=6,245) | ||||||
| Low CRF | 7 | 2.0 | 1.00 | Referent | ||
| Moderate CRF | 15 | 1.3 | 0.93 | 0.29, 2.96 | ||
| High CRF | 13 | 1.0 | 0.76 | 0.21, 2.79 | ||
| P linear trend | 0.14 | 0.62 | ||||
| Former smoker (n=15,024) | ||||||
| Low CRF | 29 | 7.3 | 1.00 | Referent | ||
| Moderate CRF | 35 | 3.4 | 0.44 | 0.26, 0.74 | ||
| High CRF | 33 | 3.3 | 0.44 | 0.24, 0.81 | ||
| P linear trend | 0.005 | 0.02 | ||||
| Current smoker (n=16,731) | ||||||
| Low CRF | 50 | 12.1 | 1.00 | Referent | ||
| Moderate CRF | 36 | 6.3 | 0.48 | 0.30, 0.76 | ||
| High CRF | 14 | 5.1 | 0.38 | 0.18, 0.79 | ||
| P linear trend | <0.001 | 0.001 | ||||
HR= hazard ratio; CI= conference interval; CRF= cardiorespiratory fitness; BMI= body mass index.
Event rate is expressed as per 10,000 person-years and adjusted for age.
adjusted for age, examination year, smoking status (never, past, or current), alcohol intake (drinks per wk), physical inactivity (yes or no), body mass index (kg/m2), and family history of cancer (present or not).
adjusted for age, examination year, cigarettes per day (for former and current smoker), alcohol intake (drinks per wk), physical inactivity (yes or not), body mass index (kg/m2), and family history of cancer (present or not).