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. 2010 Apr 19;133(5):1328–1341. doi: 10.1093/brain/awq065

Figure 1.

Figure 1

Serial extraction of water-soluble, detergent-soluble and formic acid-soluble Aβ. Human brain tissue was homogenized in 5 vol Tris-buffered saline (TBS), centrifuged at 91 000g for 78 min and the supernatant designated as the TBS extract. The pellet was re-homogenized in 5 vol of Tris-buffered saline containing 1% TX-100 (TBS-TX), centrifuged and the supernatant removed (TBS-TX extract). The remaining pellet was then extracted in 88% formic acid (FA extract).