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. 2010 Apr 16;133(5):1380–1390. doi: 10.1093/brain/awq070

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© The Author(s) 2010. Published by Oxford University Press on behalf of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Histology from hippocampus exhibiting interictal discharges with HFA. (A) Interictal discharge recorded in the ipsilateral CA3 with superimposed HFA progressing from 333 to 187 Hz. (B) Interictal discharge from the ipsilateral dentate gyrus (DG) with superimposed HFA at 362 Hz. (C) Histology of ipsilateral hippocampus showing electrode track (Nissl stain). (D) Detail of dentate gyrus histology. (E) Detail of CA3 histology. (F) Detail of CA1 histology. In A and B, top trace is raw data and the bottom is band-pass filtered 100–600 Hz. Note absence of hippocampal sclerosis and substantial neuronal loss. s.g. = stratum granulosum; s.p. = stratum pyramidale; s.o. = stratum oriens; s.r. = stratum radiatum. See also Jefferys et al. (1992).