Table 1.

Measurements of interictal and ictal epileptic discharges from ipsilateral and contralateral hippocampi of the 10 epileptic rats

Interictal	Ipsilateral HFA (n = 760)	Contralateral HFA (n = 320)	Significance (t-test)
Interictal discharge amplitude	0.76 ± 0.02 mV	1.13 ± 0.04 mV	P < 0.001
Interictal discharge duration	78 ± 1 ms	90 ± 3 ms	P < 0.001
Amplitude	0.25 ± 0.01 mV	0.34 ± 0.02 mV	P < 0.001
First spectral moment	331 ± 4 Hz	235 ± 6 Hz	P < 0.001
Second spectral moment	180 ± 2 Hz	153 ± 3 Hz	P < 0.001
Median	295 ± 4 Hz	191 ± 6 Hz	P < 0.001
Fast ripple/ripple ratio	2.77 ± 0.11	1.03 ± 0.12	P < 0.001
Ictal	(n = 92)	(n = 65)	Significance (t-test)
Amplitude	0.24 ± 0.02 mV	0.21 ± 0.02 mV	NS
First spectral moment	339 ± 8 Hz	281 ± 8 Hz	P < 0.001
Second spectral moment	188 ± 6 Hz	185 ± 4 Hz	NS
Median	293 ± 9 Hz	220.2 ± 9.1 Hz	P < 0.001
Fast ripple/ripple ratio	1.76 ± 0.16	0.87 ± 0.11	P < 0.001
Seizure onset	73%	27%

Interictal discharge amplitude and duration (first two rows) are the means and SEM of these epileptic events recorded wide-band. The bottom row indicates the percentages of seizures starting in the ipsilateral (injected) and contralateral hippocampi. All the remaining measurements are of the high frequency activity (100–600 Hz) superimposed on epileptic discharges, both interictal and ictal. Statistical tests are comparisons of ipsilateral and contralateral data. NS = not significant.