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. Author manuscript; available in PMC: 2011 Apr 22.
Published in final edited form as: J Med Chem. 2010 Apr 22;53(8):3389–3395. doi: 10.1021/jm1000979

Table 3.

Antiproliferative activity of compounds 4b, 4c, 4d, and 4e against selected cell lines in the NCI-60 screen.

GI50 (µM)
compound mean HL-60 MCF-7 MDA-MB-435
4b 21.9 1.53 8.93 3.71
4c 16.6 2.34 3.83 1.94
4d 17.8 2.37 4.16 2.12
4e 0.87 0.39 0.36 0.18