Table 1. Number of unique peptides assigned to 20 most prevalent identified proteins among samples from the parents (M, mother; F, father) and afflicted offspring (D, daughter; S, son) in Family A.
| Total Hair Shaft | Cross-Linked Fraction | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Protein | D | S | M | F | emPAI | Protein | D | S | M | F | emPAI |
| KRT86 | 86 | 86 | 90 | 87 | 36.2 | KRT32 | 18 | 15 | 15 | 13 | 14.8 |
| KRT81 | 5 | 5 | 6 | 7 | 21.5 | KRT82 | 31 | 22 | 27 | 32 | 10.4 |
| KRT83 | 9 | 5 | 2 | 11 | 9.0 | KRT35 | 22 | 16 | 20 | 22 | 10.1 |
| KRT85 | 42 | 45 | 38 | 45 | 8.2 | KRT85 | 16 | 13 | 18 | 16 | 7.2 |
| KRT33B | 48 | 43 | 56 | 39 | 7.9 | KRT86 | 27 | 31 | 36 | 26 | 6.3 |
| KRT31 | 15 | 15 | 19 | 16 | 6.0 | HIST1H4 | 9 | 6 | 7 | 5 | 5.5 |
| KRT33A | 3 | 3 | 3 | 3 | 4.5 | SFN | 10 | 11 | 10 | 11 | 4.7 |
| KRT34 | 15 | 19 | 15 | 13 | 2.3 | H2AFX | 5 | 6 | 6 | 7 | 4.3 |
| KRTAP2-2 | 13 | 13 | 11 | 12 | 0.9 | KRT34 | 4 | 6 | 9 | 5 | 3.7 |
| KRT35 | 19 | 13 | 13 | 15 | 0.6 | KRT33B | 17 | 23 | 24 | 14 | 3.3 |
| KRT32 | 10 | 9 | 10 | 10 | 0.4 | KRT31 | 5 | 9 | 8 | 6 | 2.9 |
| S100A3 | 5 | 4 | 4 | 3 | 0.3 | HIST1H2BL | 8 | 6 | 7 | 4 | 2.7 |
| KRT82 | 21 | 15 | 11 | 17 | 0.3 | S100A3 | 3 | 4 | 4 | 3 | 2.6 |
| KRTAP3-1 | 4 | 5 | 6 | 4 | 0.3 | KRTAP11-1 | 13 | 13 | 10 | 3 | 2.5 |
| H2AFX | 6 | 6 | 6 | 5 | 0.2 | VSIG8 | 16 | 10 | 10 | 18 | 2.3 |
| HIST1H2BL | 5 | 3 | 4 | 4 | 0.2 | CALML3 | 5 | 4 | 5 | 4 | 2.0 |
| KRTAP3-2 | 2 | 3 | 3 | 2 | 0.2 | KRT36 | 5 | 4 | 3 | 3 | 1.1 |
| HIST1H4 | 6 | 5 | 3 | 4 | 0.1 | PKP1 | 10 | 12 | 12 | 10 | 1.0 |
| KRT36 | 2 | 2 | 2 | 2 | 0.1 | KRT40 | 6 | 5 | 6 | 7 | 0.9 |
| KRTAP11-1 | 4 | 4 | 3 | 5 | 0.1 | PRDX6 | 2 | 5 | 4 | 6 | 0.8 |
Data include emPAI semi-quantitative estimates of relative molar amounts normalized to 100 (Ishihama et al., 2005).