Fig. 6.

Differential regulation of Jen1-GFP and Jen2-GFP in Candida albicans following phagocytosis by immune cells. A.Interaction of C. albicans with neutrophils. C. albicans cells containing ACT1-GFP, ICL1-GFP, JEN1-GFP, JEN2-GFP or the control pGFP plasmid were mixed in a 1:1 ratio with human neutrophils, and examined microscopically after 2.5 h at 37°C. Corresponding light and fluorescence images are shown. B.Interaction of C. albicans with macrophages. Cultured murine macrophages (RAW.264.7) were mixed in a 1:3 ratio with the C. albicans strains, incubated for 3 h and analysed by light and fluorescence microscopy.