TABLE I. Marker Characteristics and Single-SNP Association Results in the Family Sample.
SNP # | Name | Position | Polymorphism (minor allele) | MAF | Risk allele | FBAT | PDT | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Narrow | Intermediate | Broad | Very broad | Narrow | Intermediate | Broad | Very broad | ||||||
1 | rs1889189 | 10192086 | C/T (T) | 0.365 | T | 0.767 | 0.637 | 0.778 | 0.412 | 0.807 | 0.248 | 0.364 | 0.881 |
2 | rs6032826 | 10198817 | A/G (G) | 0.189 | G | 0.570 | 0.210 | 0.108 | 0.009 | 0.556 | 0.884 | 0.734 | 0.073 |
3 | rs6077693 | 10201917 | A/G (A) | 0.164 | G | 0.028 | 0.006 | 0.005 | 0.010 | 0.152 | 0.069 | 0.074 | 0.172 |
4 | rs3787303 | 10203748 | C/T (C) | 0.145 | C | 0.496 | 0.887 | 0.380 | 0.068 | 0.330 | 0.105 | 0.448 | 0.770 |
5 | rs2423487 | 10208095 | C/T (C) | 0.092 | C | 0.854 | 0.588 | 0.498 | 0.445 | 0.647 | 0.896 | 0.900 | 0.260 |
6 | rs6039783 | 10213034 | C/T (C) | 0.056 | C | 0.797 | 0.634 | 0.823 | 0.621 | 0.463 | 0.264 | 0.417 | 0.620 |
7 | rs363012 | 10214799 | A/G (G) | 0.351 | G | 0.734 | 0.147 | 0.191 | 0.610 | 0.597 | 0.129 | 0.210 | 0.322 |
8 | rs363043 | 10221146 | C/T (T) | 0.275 | C | 0.093 | 0.013 | 0.017 | 0.056 | 0.054 | 0.010 | 0.010 | 0.031 |
9 | rs363016 | 10226174 | C/T (T) | 0.426 | T | 0.759 | 0.408 | 0.315 | 0.112 | 0.630 | 0.882 | 0.776 | 0.284 |
10 | rs363021 | 10236811 | C/T (T) | 0.464 | T | 0.141 | 0.127 | 0.201 | 0.030 | 0.357 | 0.236 | 0.352 | 0.131 |
11 | rs362562 | 10238186 | A/G (A) | 0.414 | G | 0.100 | 0.029 | 0.069 | 0.019 | 0.325 | 0.110 | 0.199 | 0.164 |
12 | rs6039806 | 10253654 | A/C (A) | 0.494 | C | 0.230 | 0.049 | 0.185 | 0.128 | 0.185 | 0.038 | 0.123 | 0.170 |
13 | rs6077718 | 10256142 | G/T (G) | 0.126 | T | 0.282 | 0.144 | 0.223 | 0.140 | 0.426 | 0.504 | 0.587 | 0.631 |
14 | rs362993 | 10271716 | C/T (T) | 0.118 | C | 0.064 | 0.105 | 0.224 | 0.139 | 0.132 | 0.273 | 0.494 | 0.434 |
15 | rs362988 | 10276370 | A/G (A) | 0.456 | G | 0.013 | 0.012 | 0.014 | 0.004 | 0.159 | 0.092 | 0.074 | 0.030 |
16 | rs6039820 | 10277027 | C/T (T) | 0.481 | C | 0.005 | 0.004 | 0.002 | 0.002 | 0.007 | 0.002 | 0.001 | 0.004 |
17 | rs8636 | 10282742 | C/T (T) | 0.303 | C | 0.206 | 0.181 | 0.124 | 0.525 | 0.289 | 0.334 | 0.259 | 0.437 |
18 | rs6133852 | 10285960 | A/G (A) | 0.032 | G | 0.176 | 0.067 | 0.036 | 0.006 | 1.000 | 0.387 | 0.223 | 0.024 |
Bold type denotes P < 0.05.