Table 2.
Pre-immunosuppression (Day 400) |
Post-immunosuppression (Day 414 and 420) |
||||
---|---|---|---|---|---|
Group (n = 3) |
Blood | Lymph Node | Blood | Lymph Node | Bone Marrow |
Group E | 3/3 | 3/3 | 3/3 | 2/2 | 2/3 |
Group E+doxy | 0/3 | 0/3 | 0/3 | 0/2 | 0/3 |
Group A→E | 3/3 | 3/3 | 3/3* | 2/2 | 1/3 |
Group A→E+doxy | 0/3 | 0/3 | 0/3 | 0/3 | 0/3 |
Group E→A | 3/3 | 3/3 | 3/3 | 3/3 | 3/3* |
Group E→A+doxy | 0/3 | 0/3 | 0/3 | 0/3 | 0/3 |
Group A+E | 3/3 | 3/3 | 3/3* | 3/3 | 2/3* |
Group A+E+doxy | 0/3 | 0/3 | 0/3 | 0/3 | 0/2 |
Untreated control dogs are compared to the doxycycline treated dogs (+doxy). Doxycycline was administered between days 211 and 238. Dexamethasone was administered between days 410 and 414. (Number of dogs testing PCR positive/number tested in each group.*Indicates those groups where PCR results for individual samples disagreed between the methods.)