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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Invest Radiol. 2009 Aug;44(8):433–439. doi: 10.1097/RLI.0b013e3181a4d7e9

Figure 5. Effects of LY294002 on ERK phosphorylation in Omniscan-treated cells.

Figure 5

Cells were incubated under control conditions or in the presence of Omniscan with or without U0126 or LY294002 for three days for the indicated times. At the end of the incubation period, cell lysates were prepared and assayed for phosphor-ERK by western blotting. Values shown are means and standard errors based on n=3 separate experiments. The inset shows phosphor-ERK and from one of the replicate experiments. Statistical significance of the data was assessed by ANOVA, followed by paired-group comparisons. *indicates statistically significant decrease compared to Omniscan alone at p<0.05 level.