Table 6.

Cholesterol synthesis genes in Little mice

Gene	Description	Fold-change*	P-value†
Cyp51	Lanosterol demethylase	2.2	0.0379
Fdft1	Squalene synthetase	2.7	0.0008
Fdps	Farnesyl pyrophosphate synthetase	1.3	0.3662
Hmgcr	3-hydroxy-3-methylglutaryl-coenzyme A reductase	5.3	0.0668
Hmgcs	Hydroxymethylglutaryl-CoA synthase	3.1	0.0166
Mvd	Diphosphomevalonate decarboxylase	2.3	0.0461
Mvk	Mevalonate kinase	1.9	0.0052
Sqle	Squalene epoxidase	2.4	0.0500

^*The fold-change refers to the ratio of the expression values of Little mice over the wild-type mice obtained by real-time PCR analysis.

^†The P-value refers to a Student’s t-test for the difference in expression between Little and wild-type mice.