Proliferation and migration of cultured VSMCs, as determined by cell counter (A), MTT assay (B), and modified Boyden chamber (C). A, after a 3-day culture, the number of SHR-derived VSMCs was much higher than WKY-derived VSMCs. B and C, the SHR-derived VSMCs showed enhanced proliferative (B) and migratory (C) capacities compared with WKY-derived VSMCs. Data are presented as mean ± S.E. (n = 5). *, p < 0.05 versus WKY-VSMC.