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Western blot analysis of total Serca2a, phosphorylated phospholamban (p-PLB), and NCX1 in the heart. Membrane protein extracts (100 μg) obtained from 10-month-old wild type and TEAD-1 Tg L12 hearts revealed a significant decrease in the total level of Serca2a protein, the phosphorylation of phospholamban, and increased NCX1 protein (n = 4).
