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Time course of fetal gene expression
Quantitative reverse transcription-PCR analysis of fetal gene mRNA expression in fetal, neonatal, and adult TEAD-1 Tg hearts (line 12) shows the re-expression of gene programs in neonatal and adult mice (fold change).
| WT | 14-Day fetal, n = 12 | 2-day neonatal, n = 7 | 5 months, n = 5 | 10 months, n = 3 | |
|---|---|---|---|---|---|
| ANP | 1 | 1.1 | 1.4 | 3.0 | 49.7 |
| BNP | 1 | 1.0 | 1.6 | 2.1 | 24.4 |
| α-MHC | 1 | 0.3 | 0.8 | 0.8 | 0.2 |
| β-MHC | 1 | 1.5 | 2.2 | 8.7 | 7.4 |
| α-sk-actin | 1 | 2.1 | 8.7 | 12.7 | 18.0 |
| TEAD-1 | 1 | 5.4 | 3.4 | 12.1 | 9.3 |
