Table III.
Selected studies of persons exposed occupationally to protracted low-LET external ionizing radiation. Estimates based on A-bomb survivors shown for comparison.
| Description of study | Mean dose | Health endpoints studied | ERR Gy−1 (or Sv−1) for leukemia excluding CLL (90% CI) | ERR Gy−1 (or Sv−1) for all cancers excluding leukemia (90% CI) | References |
|---|---|---|---|---|---|
| Nuclear workers in 15 countries | 19.4 mSv | Cause-specific mortality | 1.9 (<0, 7.1) 196 deaths |
0.97 (0.27, 1.80) 5024 deathsa |
Cardis et al. 2007 |
| Nuclear workers enrolled in the United Kingdom National Registry for Radiation Workers (NRRW) | 24.9 mSv | Cause-specific mortality and cancer incidence | 1.7 (0.06, 4.3) 198 deaths |
0.28 (0.02, 0.56) 7455 deaths |
Muirhead et al. 2009 |
| Chornobyl liquidators in Ukraine | 76.4 mGy | Leukemia incidence | 3.4a (0.5, 9.8) 71 cases |
Not applicable | Romanenko et al. 2008 |
| Chornobyl liquidators in Belarus, Russian Federation, and Baltic countries | 13 mGy (median) | Leukemia incidence | 4.8a (−0.2, 0.24) 40 cases |
Not applicable | Kesminiene et al. 2008 |
| Workers at the Mayak nuclear facility in the Russian Federation | ∼500 mGy | Cause-specific mortality | Significant dose-response (p < 0.001) 49 deaths |
Significant dose-response (p < 0.001) 1062 deaths from solid cancers other than lung, liver, and bone. |
Shilnikova et al. 2003 |
| Male A-bomb survivors exposed between the ages of 20 and 60 years | Cause-specific mortality | 1.5 (−0.8,4.6) 83 deaths |
0.32c (0.07,0.47) 3259 deaths |
Cardis et al. 2007 |
Dose units are those used in the respective papers. The two Chornobyl studies are case-control studies; the remainder are cohort studies.
Estimates are for all leukaemia, including CLL.
Estimate is based on a linear-quadratic model. Estimate based on a linear model is 3.15 (1.8,5.2)