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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Int J Radiat Biol. 2009 Jun;85(6):467–482. doi: 10.1080/09553000902883836

Table III.

Selected studies of persons exposed occupationally to protracted low-LET external ionizing radiation. Estimates based on A-bomb survivors shown for comparison.

Description of study Mean dose Health endpoints studied ERR Gy−1 (or Sv−1) for leukemia excluding CLL (90% CI) ERR Gy−1 (or Sv−1) for all cancers excluding leukemia (90% CI) References
Nuclear workers in 15 countries 19.4 mSv Cause-specific mortality 1.9 (<0, 7.1)
196 deaths
0.97 (0.27, 1.80)
5024 deathsa
Cardis et al. 2007
Nuclear workers enrolled in the United Kingdom National Registry for Radiation Workers (NRRW) 24.9 mSv Cause-specific mortality and cancer incidence 1.7 (0.06, 4.3)
198 deaths
0.28 (0.02, 0.56)
7455 deaths
Muirhead et al. 2009
Chornobyl liquidators in Ukraine 76.4 mGy Leukemia incidence 3.4a (0.5, 9.8)
71 cases
Not applicable Romanenko et al. 2008
Chornobyl liquidators in Belarus, Russian Federation, and Baltic countries 13 mGy (median) Leukemia incidence 4.8a (−0.2, 0.24)
40 cases
Not applicable Kesminiene et al. 2008
Workers at the Mayak nuclear facility in the Russian Federation ∼500 mGy Cause-specific mortality Significant dose-response (p < 0.001)
49 deaths
Significant dose-response (p < 0.001)
1062 deaths from solid cancers other than lung, liver, and bone.
Shilnikova et al. 2003
Male A-bomb survivors exposed between the ages of 20 and 60 years Cause-specific mortality 1.5 (−0.8,4.6)
83 deaths
0.32c (0.07,0.47)
3259 deaths
Cardis et al. 2007

Dose units are those used in the respective papers. The two Chornobyl studies are case-control studies; the remainder are cohort studies.

a

Estimates are for all leukaemia, including CLL.

b

Estimate is based on a linear-quadratic model. Estimate based on a linear model is 3.15 (1.8,5.2)