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. Author manuscript; available in PMC: 2011 Mar 17.
Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2010 Jan 13;34(2):376–386. doi: 10.1016/j.pnpbp.2010.01.004

Table 3.

The representative parameters of water maze performance in the probe trial of the Zolpidem (ZOL) dose-response experiment. The key to regions used in the analysis is given in Fig. 1.

ZOL 0.5 ZOL 1.0 ZOL 2.0 ANOVA, F(2,21) P
Whole water maze parameters
Distance (m±SEM) 10.93±0.97 11.50±0.96 12.75±0.56 1.187 0.325
Platform quadrant (NE) parameters
Distance (m±SEM) 2.41±0.29 2.18±0.51 2.22±0.44 0.083 0.920
Time (s±SEM) 11.86±1.44 9.64±1.92 9.75±2.06 0.471 0.631
Peripheral ring parameters
Distance (m±SEM) 4.16±0.61 6.09±0.89 7.85±0.82* 5.564 0.012
Time (s±SEM) 33.48±3.68 39.86±1.67 42.80±3.35 2.473 0.109
Platform ring parameters
Distance (m±SEM) 5.27±0.68 4.48±0.31 4.00±0.65 1.247 0.308
Time (s±SEM) 21.46±3.05 17.31±1.38 14.50±2.60 2.049 0.154
Target region parameters
Distance (m±SEM) 1.51±0.27 1.12±0.14 0.99±0.22 1.520 0.242
Time (s±SEM) 7.26±1.36 4.03±0.52* 3.51±0.76* 4.596 0.022
Platform parameters
Number of entries (±SEM) 1.25±0.41 0.38±0.18 0.50±0.19 2.813 0.083
Distance (m±SEM) 0.097±0.031 0.047±0.028 0.053±0.023 0.945 0.405
*

P<0.05 compared to ZOL 0.5 group.