FIG. 5.

Micro-MRI demonstrated cerebral artery development from E12.5 to E17.5. Views from the back (caudal; left panels) and side (lateral; right panels) show the cerebral vasculature of E12.5 (top panels), E15.5 (middle), and E17.5 (bottom panels) embryos using the first-pass retrograde perfusion method. Venous structures were most effectively eliminated at E17.5, but the major cerebral arteries were easily visualized at all three stages. Abbreviations: basilar artery, BA; anterior inferior cerebellar artery, AICA; posterior cerebral artery, PCA posterior communicating artery, PComA; middle cerebral artery, MCA; anterior cerebral artery, ACA; internal carotid arteries, ICA; vertebral arteries, VA. Scale bars = 1 mm.