Figure 4.
Apoptosis and proliferation indexes in papillomas of transgenic and wild type sibling mice.
BrdU and TUNEL assays were done on paraffin embedded section from papillomas of K5-CDK4 (line 2303) and wild type mice. The numbers of BrdU and TUNEL positive cells were determined per 25 μm2 of tumor area from K5-CDK4 (solid bars) and wild type siblings (empty bars) mice.