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Decreased translational efficiency due to loss of kinetoplastid-specific ribose cap methylation. A. Graph of [35S]-methionine incorporation into proteins in TbMTr1 knockout cells. B. Graph of [35S]-methionine incorporation in TbMTr3 knockout cells. C. Graph of [35S]-methionine incorporation in TbMTr2−/−/TbMTr3−/− double knockout cells. The bars represent the range of results from two independent experiments.
