Table 2.
Case # | Diagnosis | HPV | EBV | KSHV | CMV | BK | JC | HSV 1/2 |
---|---|---|---|---|---|---|---|---|
1 | OSSN | + | + | - | - | - | - | + |
2 | Pterygium | + | + | + | + | - | - | + |
3 | OSSN | + | + | + | + | - | - | + |
4 | OSSN | + | + | + | - | - | - | + |
5 | OSSN | + | + | - | + | - | - | + |
6 | OSSN | + | + | + | + | - | - | + |
8 | OSSN | + | + | + | - | - | - | + |
9 | OSSN | + | + | - | - | - | - | + |
11 | OSSN | + | + | + | - | - | - | - |
12 | OSSN | + | + | + | - | - | - | - |
13 | OSSN | -/+ | + | - | + | - | - | - |
14 | OSSN | - | - | + | + | - | - | + |
15 | Pterygium | - | + | + | + | - | - | + |
16 | Pterygium | - | + | - | + | - | - | + |
17 | Pterygium | - | + | + | - | - | - | + |
18 | OSSN | - | + | + | + | - | - | + |
19 | OSSN | - | + | + | - | - | - | - |
21 | OSSN | - | + | + | - | - | - | - |
22 | OSSN | - | + | - | - | - | - | - |
23 | OSSN | - | + | + | + | - | - | + |
24 | OSSN | - | + | + | + | - | - | - |
25 | Pterygium | - | + | - | + | - | - | + |
26 | Pterygium | + | - | + | + | - | - | - |
27 | Pterygium | + | + | + | - | - | - | + |
28 | OSSN | + | + | - | - | - | - | + |
29 | OSSN | + | - | + | + | - | - | + |
30 | Pterygium | + | + | - | + | - | - | - |
31 | OSSN | + | + | + | + | - | - | + |
32 | OSSN | - | + | - | + | - | - | + |
33 | OSSN | + | - | + | + | - | - | + |
34 | OSSN | + | + | + | - | - | - | - |
35 | OSSN | + | - | + | - | - | - | - |
36 | OSSN | + | + | - | + | - | - | + |
37 | OSSN | + | - | + | + | - | - | + |
38 | OSSN | + | + | + | + | - | - | + |
39 | OSSN | + | + | + | + | - | - | + |
Oncogenic viruses identified in each OSSN and pterygium patient as determined by PCR analysis. Most cases tested positive for HPV, EBV, KSHV, and HSV. HPV results for samples 14-24 were intriguing since most were positive on IHC and ISH. None was positive for BK and JC.