Table 2.
Covariate | n (%) | Median time to evaluation (years) (interquartile range) | Unadjusted HR (95% CI) | Adjusted HR (95% CI) |
---|---|---|---|---|
Age | ||||
<40 years old | 110 (44) | 3.12 (1.78–4.86) | Ref | |
≥40 years old | 138 (56) | 2.88 (1.57–5.48) | 1.01 (0.98–1.04) | |
Gender | ||||
Female | 52 (21) | 3.25 (2.04–4.66) | Ref | |
Male | 196 (79) | 2.94 (1.40–5.12) | 1.02 (0.68–1.52) | |
Race/Ethnicity (%) | ||||
White | 158 (64) | 2.88 (1.40–4.76) | Ref | Ref |
African American | 59 (24) | 4.16 (1.79–5.54) | 0.66 (0.44–0.99) | 0.68 (0.45–1.02) |
Hispanic | 20 (8) | 3.58 (2.03–4.78) | 0.75 (0.43–1.30) | 0.80 (0.45–1.41) |
Alaska Native/American Indian | 11 (4) | 2.26 (1.15–n/a) | 1.25 (0.45–3.42) | 1.35 (0.49–3.74) |
CD4 cell count (cells/μL)a | ||||
≥200 | 141 (57) | 2.70 (1.65–4.71) | Ref | Ref |
<200 | 106 (43) | 3.79 (1.34–5.39) | 0.81 (0.58–1.13) | 0.83 (0.58–1.18) |
HIV RNA level (copies/mL)b | ||||
<500 | 75 (30) | 3.47 (1.65–4.45) | Ref | |
500–10,000 | 55 (22) | 3.47 (1.57–5.33) | 0.89 (0.52–1.51) | |
>10,000 | 117 (47) | 2.77 (1.58–5.17) | 0.93 (0.59–1.46) | |
Antiretroviral therapyc | ||||
No | 160 (65) | 2.84 (1.57–5.12) | Ref | |
Yes | 85 (35) | 3.51 (1.86–4.90) | 0.84 (0.56–1.26) | |
History of substance abuse | ||||
No | 62 (25) | 3.68 (1.33–5.20) | Ref | |
Yes | 186 (75) | 2.88 (1.61–4.97) | 0.99 (0.67–1.42) | |
History of mental health diagnosis | ||||
No | 124 (50) | 2.77 (1.61–4.65) | Ref | |
Yes | 124 (50) | 3.49 (1.51–5.17) | 1.04 (0.74–1.46) |
Nadir CD4 count considered at time of first HCV RNA test, data not available for 1 patient.
Most recent HIV RNA test considered at time of first HCV RNA test. Data available within 6 months for 201/248 (83%) of patients. Data not available for 1 patient.
On highly active antiretroviral therapy within 6 months of first HCV RNA test; data not available for 3 patients.
n/a, not available; HCV, hepatitis C virus.