Table 2.
Genotype and allele frequencies for the LCE3C_LCE3B-del (parentheses indicate frequencies).
| LCE3 genotypes | Alleles | ||||
|---|---|---|---|---|---|
| II | ID | DD | D | I | |
| Controls (n = 400) |
60 (15) |
196 (51) |
144 (36) |
493 (0.61) |
307 (0.39) |
| Total patients (n = 405) |
52 (13) |
204 (50) |
149 (37) |
502 (0.62) |
308 (0.38) |
| Psor. Vulgaris (n = 324) |
30 (9) |
157 (49) |
137 (42) |
431 (0.67) |
217 (0.33) |
| Familial Ps (n = 221) |
32 (14) |
113 (51) |
76 (34) |
265 (0.60) |
177 (0.40) |
| Sporadic Ps (n = 184) |
20 (11) |
91 (50) |
73 (39) |
237 (0.64) |
131 (036) |
| Early onset Ps (n = 243) |
32 (13) |
124 (51) |
87 (36) |
298 (0.61) |
188 (0.39) |
| Late onset Ps (n = 162) |
20 (12) |
77 (48) |
65 (40) |
207 (0.64) |
117 (0.36) |
| Non Severe Ps (n = 243) |
28 (11) |
126 (52) |
89 (37) |
304 (0.63) |
182 (0.37) |
| Severe Ps (n = 162) |
24 (15) |
78 (48) |
60 (37) |
198 (0.61) |
126 (0.39) |
| Arthritis (n = 83) |
8 (10) |
49 (59) |
26 (31) |
101 (0.61) |
65 (0.39) |
| Non arthritis (n = 322) |
44 (14) |
155 (45) |
123 (41) |
401 (0.62) |
243 (0.38) |
| Cw6 positive (n = 158) |
11 (8) |
81 (51) |
66 (42) |
213 (0.67) |
103 (0.33) |
| Cw6 negative (n = 247) |
40 (16) |
123 (50) |
84 (34) |
291 (0.59) |
203 (0.41) |
| Psor. Vulgaris Non arhritis (n = 274) |
25 (9) |
128 (47) |
121 (44) |
370 (0.68) |
178 (0.32) |