Table 1.
Presence of fhu genes in sequenced H. influenzae strains
| Strain | Sourcea | Typeb | GenBank Accession No.c | fhu locusd |
|---|---|---|---|---|
| Rd KW20 | - | nt | L42023.1 | No |
| 86-028NP | NP AOM | nt | CP000057.2 | No |
| PittEE | MEE COM | nt | CP000671.1 | Yes |
| PittGG | Ext. Ear Ott. | nt | CP000672.1 | No |
| 22.1-21 | NP Healthy | nt | AAZD00000000 | No |
| 22.4-21 | NP Healthy | nt | AAZJ00000000 | Yes |
| 3655 | MEE AOM | nt | AAZF00000000 | No |
| 6P18H1 | Adult COPD | nt | AAWW00000000 | No |
| 7P49H1 | Adult COPD | nt | AAWV00000000 | Yes |
| PittAA | MEE COM | nt | AAZG00000000 | Yes |
| PittHH | MEE COM | nt | AAZH00000000 | No |
| PittII | MEE COM | nt | AAZI00000000 | No |
| R2866 | BLD | nt | AADP00000000 | No |
| R3021 | NP Healthy | nt | AAZE00000000 | Yes |
| 10810 | Meningitis | b | na | No |
| F3031 | BPF Clone | aegyptius | na | No |
| F3047 | BPF Clone | aegyptius | na | No |
a Site and/or disease state from which strain isolated; NP, nasopharynx, AOM, acute otitis media; MEE, middle ear effusion; COM, chronic otitis media; Ext. Ear Ott, Isolate from external ear in patient with ottorhea; Healthy, Healthy child; COPD, chronic obstructive pulmonary disease; BLD, blood. No source is given for Rd KW20 since this a laboratory strain that has been passaged multiple times since its original isolation [63,74,75].
b nt, nontypeable strain; b, type b strain; aegyptius, H. influenzae biogroup aegyptius.
c GenBank Accession Numbers beginning with L or C denote completed genomic sequence, those beginning with AA denote sequences in process of assembly. na, not available (no GenBank accession numbers are available, sequences are accessible at the Wellcome Trust Sanger Institute [43]).
d Yes, fhu locus is present; No, fhu locus is absent.