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. 2010 Apr 26;5(4):e10358. doi: 10.1371/journal.pone.0010358

Table 3. Cell ploidy as determined by fluorescence in situ hybridization.

Sample No. Cellular Component Triploid (%) Tetraploid (%) No. Probes
13 Surface (n = 47) 0 0 6
Cyst (n = 85) 9 (10.6) 4 (4.7) 5
37 Cyst (n = 44) 14 (31.8) 1 (2.3) 4
59 Surface (n = 9) 0 0 3
Cyst (n = 161) 14 (8.7) 2 (1.2) 6
84 Surface (n = 45) 0 0 6
Cyst (n = 135) 5 (3.7) 0 6
86 Surface (n = 56) 1 (1.8) 0 3
Cyst (n = 36) 1 (2.8) 0 5
102 Surface (n = 96) 0 0 4
Cyst (n = 43) 2 (4.7) 0 3
112 Surface (n = 11) 0 0 3
Cyst (n = 139) 10 (7.2) 2 (1.4) 6
131 Surface (n = 36) 1 (2.8) 0 5
Cyst (n = 46) 6 (13.0) 2 (4.3) 5
135 Surface (n = 40) 0 0 5
Cyst (n = 90) 4 (4.4) 0 6
140 Surface (n = 29) 0 0 3
Cyst (n = 34) 1 (2.9) 0 3
183 Surface (n = 41) 0 0 4
Cyst (n = 67) 4 (6.0) 0 5
Total Ovaries Total Cell Type Total Triploid (%) Total Tetraploid (%) Total % Aneuploid
11 Surface (n = 410) 2 (0.5) 0 0.5
Cyst (n = 880) 70 (7.9) 11 (1.3) 9.2

The number of surface epithelial cells and number of cystic epithelial cells available for quantitation for each ovarian specimen are listed, followed by the number (percentage) of nuclei showing triploidy or tetraploidy for at least one of the indicated number of probes. Statistical analysis of these data is described in the Materials and Methods section; the difference between total percentage of aneuploid cells in cyst vs. surface epithelial cells is significant at a value of P<0.001.