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P < 0.001 for BRAF and KRAS comparisons among CRC groups. P = 0.001 for codon 12 and P = 0.033 for codon 13 comparisons among groups.
| BRAF mutation | KRAS mutation | codon 12 | codon 13 | |
|---|---|---|---|---|
| MSS HNPCC | 0% | 31.8% (7) | 31.8% (7) | 0% |
| Lynch syndrome | 0% | 9.5% (2) | 9.5% (2) | 0% |
| MSI sporadic | 28.3% (13) | 4.4% (2) | 2.2% (1) | 2.2% (1) |
| MSS sporadic | 2.2% (2) | 39.2% (36) | 27.2% (25) | 12% (11) |
