Table 5. LINE-1 methylation according to other molecular features and clinical data.

Mean Rank value when applying the Mann-Witney U test. *T test applied

	Mean % LINE-1 methylation	Mean Rank
MI			P = 0.003
high	68.17 (138)	109.66
low	64.42 (37)	82.19
MS status			P = 0.007
MSI	66.97 (65)	102.15
MSS	64.18 (111)	80.51
KRAS			P = 0.441
wild type	65.22 (130)	90.26
mutant	65.18 (46)	83.52
BRAF*			P = 0.494
wild type	65.09 (160)
mutant	66.32 (15)
Gender*			P = 0.272
male	64.70 (95)
female	65.80 (81)
Location			P = 0.001
right	67.10 (81)	99.69
left	63.53 (90)	73.68
Age			P = 0.064
≤50	64.77 (32)	85.86
50-70	63.35 (51)	75.77
≥70	66.37 (93)	96.39