Table 6. LINE-1 methylation in hereditary and sporadic CRC tumors.
Mean Rank value when applying the Kruskal-Wallis test. P values for comparison between MSS HNPCC and the other types of CRC, using the Mann-Witney U test. We performed a total of 3 comparisons, therefore differences were statistically significant when be P<(.05/3)=<.017.
Mean % LINE1 methylation | Mean Rank | P | |
---|---|---|---|
MSS HNPCC | 60.08 (21) | 56.05 | |
Lynch syndrome | 66.29 (20) | 94.80 | 0.015 |
MSI sporadic | 67.27 (45) | 105.41 | 0.001 |
MSS sporadic | 65.13 (90) | 86.22 | 0.009 |