Table 2.

Transcription-regulating long non-coding RNAs

	Long noncoding RNA	Function	Refs
Specific Transcription Factors	SRA	forms a ribonucleoprotein complex with steroid hormone receptors (SHRs) to co-activate transcription	57,58
	Evf-2	recruits Dlx, a homeodomain transcription factor, and MECP2 to key intergenic DNA regulatory elements, regulating Dlx5 and Dlx6 expression	43,44
	HSR-1	in response to heat shock, allows for the trimerization of the heat shock factor-1 (HSF-1), which then binds to the translation- elongation factor 1A (eIF1A) to initiate heat shock protein expression	59
	RNA upstream of CCND1	forms a complex with the RNA-binding protein, TLS, facilitating the repression of CCND1 by the chromatin binding protein (CBP) and p300	60
	LXRBSV	acts as a transcriptional co-activator with liver X receptor (LXR)-β to enhance receptor- mediated transactivation	61
General Transcription Factors	7SK	forms a complex with hexamethylenes bisacetamide-induced protein-1 (HEXIM1), which then binds to PTEFb, thereby preventing transcriptional elongation by RNA polymerase II	62–64
	RNA upstream of DHFR	creates a triplex structure in the core promoter of DHFR, blocking the binding of TFIID and repressing transcription	65
RNAP II	Alu Elements	binds to RNA polymerase II, blocking transcription	66