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. Author manuscript; available in PMC: 2011 May 14.
Published in final edited form as: J Mol Biol. 2010 Mar 20;398(4):530–541. doi: 10.1016/j.jmb.2010.03.026

Table 3.

Affinities of HBcAg and HBeAg binding to Mabs

Ligand Analyte ka (1/Ms) kd (1/s) Kd (M)
Mab 904 Cp183c 2.5 × 104 4.3 × 10-4 1.7 × 10-8
Cp149c 5.3 × 104 8.2 × 10-4 1.5 × 10-8
Cp(-10)149c 1.2 × 104 3.0 × 10-4 2.6 × 10-8
Cp149d 2.5 × 104 8.4 × 10-5 3.4 × 10-9
Cp(-10)149d 6.9 × 104 2.4 × 10-4 3.5 × 10-9
Mab 905 Cp183c 5.2 × 104 4.3 × 10-5 8.4 × 10-10
Cp149c 2.3 × 105 2.3 × 10-4 1.0 × 10-9
Cp(-10)149c 4.0 × 104 5.5 × 10-4 1.4 × 10-8
Cp149d 3.7 × 103 1.6 × 10-3 4.4 × 10-7
Cp(-10)149d 1.9 × 105 3.8 × 10-5 2.0 × 10-10
Mab 3105 Cp183c 4.1 × 104 1.4 × 10-3 3.4 × 10-8
Cp149c 2.2 × 105 1.1 × 10-3 4.9 × 10-9
Cp(-10)149c 1.4 × 104 4.6 × 10-5 3.2 × 10-9
Cp149d 5.1 × 104 1.7 × 10-3 3.3 × 10-8
Cp(-10)149d 3.5 × 104 1.2 × 10-2 3.4 × 10-7
Mab 3120 Cp183c 1.5 × 104 3.6 × 10-7 2.3 × 10-11
Cp149c 3.0 × 104 3.8 × 10-7 1.2 × 10-11
Cp(-10)149c 1.2 × 104 2.4 × 10-7 1.9 × 10-11
Mab F11A4 Cp183c 2.9 × 104 2.7 × 10-5 9.4 × 10-10
Cp149c 1.8 × 106 1.8 × 10-4 1.0 × 10-10
Cp(-10)149c 1.0 × 104 1.4 × 10-6 1.3 × 10-10
Cp149d 5.7 × 105 3.9 × 10-3 6.9 × 10-9
Cp(-10)149d 5.3 × 104 7.5 × 10-3 1.4 × 10-7
Mab e6 Cp149d 6.5 × 104 2.2 × 10-4 3.3 × 10-9
Cp(-10)149d 5.9 × 103 6.9 × 10-4 1.2 × 10-7