Table 3.
Ligand | Analyte | ka (1/Ms) | kd (1/s) | Kd (M) |
---|---|---|---|---|
Mab 904 | Cp183c | 2.5 × 104 | 4.3 × 10-4 | 1.7 × 10-8 |
Cp149c | 5.3 × 104 | 8.2 × 10-4 | 1.5 × 10-8 | |
Cp(-10)149c | 1.2 × 104 | 3.0 × 10-4 | 2.6 × 10-8 | |
Cp149d | 2.5 × 104 | 8.4 × 10-5 | 3.4 × 10-9 | |
Cp(-10)149d | 6.9 × 104 | 2.4 × 10-4 | 3.5 × 10-9 | |
Mab 905 | Cp183c | 5.2 × 104 | 4.3 × 10-5 | 8.4 × 10-10 |
Cp149c | 2.3 × 105 | 2.3 × 10-4 | 1.0 × 10-9 | |
Cp(-10)149c | 4.0 × 104 | 5.5 × 10-4 | 1.4 × 10-8 | |
Cp149d | 3.7 × 103 | 1.6 × 10-3 | 4.4 × 10-7 | |
Cp(-10)149d | 1.9 × 105 | 3.8 × 10-5 | 2.0 × 10-10 | |
Mab 3105 | Cp183c | 4.1 × 104 | 1.4 × 10-3 | 3.4 × 10-8 |
Cp149c | 2.2 × 105 | 1.1 × 10-3 | 4.9 × 10-9 | |
Cp(-10)149c | 1.4 × 104 | 4.6 × 10-5 | 3.2 × 10-9 | |
Cp149d | 5.1 × 104 | 1.7 × 10-3 | 3.3 × 10-8 | |
Cp(-10)149d | 3.5 × 104 | 1.2 × 10-2 | 3.4 × 10-7 | |
Mab 3120 | Cp183c | 1.5 × 104 | 3.6 × 10-7 | 2.3 × 10-11 |
Cp149c | 3.0 × 104 | 3.8 × 10-7 | 1.2 × 10-11 | |
Cp(-10)149c | 1.2 × 104 | 2.4 × 10-7 | 1.9 × 10-11 | |
Mab F11A4 | Cp183c | 2.9 × 104 | 2.7 × 10-5 | 9.4 × 10-10 |
Cp149c | 1.8 × 106 | 1.8 × 10-4 | 1.0 × 10-10 | |
Cp(-10)149c | 1.0 × 104 | 1.4 × 10-6 | 1.3 × 10-10 | |
Cp149d | 5.7 × 105 | 3.9 × 10-3 | 6.9 × 10-9 | |
Cp(-10)149d | 5.3 × 104 | 7.5 × 10-3 | 1.4 × 10-7 | |
Mab e6 | Cp149d | 6.5 × 104 | 2.2 × 10-4 | 3.3 × 10-9 |
Cp(-10)149d | 5.9 × 103 | 6.9 × 10-4 | 1.2 × 10-7 |