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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: J Autoimmun. 2009 Dec 24;34(4):453–459. doi: 10.1016/j.jaut.2009.11.017

Figure 7. The αMβ2-binding defective mutant γC390polyA effectively inhibits EAE.

Figure 7

EAE was induced using the same protocol as in Figure 4. γC399tr and γC390polyA were able to effectively inhibit EAE (7A upper left and 7B upper right, respectively. Asterix represents P<0.05, student T test). 7C) Lower left- mice treated with buffer alone as a control developed severe EAE. 7D) Lower right- animals that had initially developed EAE were able to recover after administration of γC399tr. This figure better highlights the chronic nature of the untreated animals.