Table 1.
Stage-specific multivariate Cox regression on disease-specific survival for melanoma patients (n=40,520) from SEER (1988–2000)
| I (n=32,430) | II (n=5,089) | III (n=1,963) | IV (n=1,038) | |
|---|---|---|---|---|
| Characteristic | HR (95%CI) | HR (95%CI) | HR (95%CI) | HR (95%CI) |
| Age | ||||
| < 50 years (ref) | 1 | 1 | 1 | 1 |
| ≥ 50 | 1.60(1.44–1.78) | 1.56(1.39–1.74) | 1.60(1.40–1.82) | 1.31(1.11–1.56) |
| Sex | ||||
| Female (ref) | 1 | 1 | 1 | 1 |
| Male | 1.50(1.34–1.67) | 1.49(1.33–1.67) | 1.24(1.07–1.42) | 1.08(0.92–1.27) |
| Race | ||||
| White (ref) | 1 | 1 | 1 | 1 |
| Non-White | 0.37(0.25–0.55) | 0.83(0.62–1.12) | 0.92(0.64–1.31) | 0.74(0.48–1.15) |
| Marital status | ||||
| Married (ref) | 1 | 1 | 1 | 1 |
| Unmarried | 1.29(1.15–1.45) | 1.16(1.04–1.29) | 1.24(1.09–1.42) | 1.25(1.06–1.46) |
| Unknown | 0.40(0.34–0.47) | 0.66(0.55–0.80) | 0.98(0.69–1.40) | 1.00(0.67–1.49) |
| Histology | ||||
| Superficial (ref) | 1 | 1 | 1 | 1 |
| Nodular | 4.32(3.72–5.03) | 1.11(0.97–1.27) | 1.36(1.12–1.65) | 1.09(0.65–1.84) |
| Acral | 2.48(1.59–3.86) | 1.28(0.97–1.69) | 1.47(1.00–2.15) | 1.06(0.45–2.45) |
| Other/Unknown | 1.26(1.13–1.40) | 0.86(0.75–0.98) | 1.21(1.02–1.45) | 1.19(0.75–1.87) |
| Location | ||||
| Upper Extremity (ref) | 1 | 1 | 1 | 1 |
| Lower Extremity | 1.06(0.89–1.26) | 1.29(1.10–1.52) | 1.11(0.89–1.38) | 0.87(0.58–1.29) |
| Trunk | 1.54(1.34–1.77) | 1.46(1.27–1.68) | 1.13(0.92–1.38) | 1.37(0.97–1.94) |
| Head & Neck | 1.68(1.44–1.96) | 1.30(1.11–1.51) | 1.36(1.09–1.70) | 1.09(0.76–1.57) |
| Other | 1.54(0.82–2.89) | 0.94(0.46–1.90) | 1.42(1.07–1.89) | 1.29(0.95–1.75) |