Table 3.
Sex differences according to the three selected articles with crystal-proven gout
| Puig [18] | Lally [16] | Gallerani [17] | |
|---|---|---|---|
| Year | 1991 | 1986 | 1999 |
| Score | 3.5 | 3 | 2.5 |
| Female | 35 | 23 | 14 |
| Female% | 14 | 23 | 7 |
| Male (n) | 220 | 75 | 196 |
| Study population | |||
| Population | Hospital | Hospital | Hospital |
| Diagnose | Syn.tap/ACR | Syn.tap | Syn.tap |
| Ethnicity | Caucasian | Mixed | Caucasian |
| Postmenopausal at onset, n (%) | 30 (86) | 21(92) | – |
| Average age of women (years) | 67 | 58 | 68 |
| Average age of men (years) | 58 | 50 | 56 |
| Age of onset | F + 12 | F + 9 | F + 12 |
| Duration | M* | M | – |
| Patients characteristics (% women–% men) | |||
| Diuretics | F* (57–14)* | F* (83–47) | – |
| Alcohol | M* (14–55) | M* (10–45) | – |
| Obesity | E | – | – |
| Familiar gout | – | E | - |
| Spring peak | – | – | M** |
| Recurrence | – | – | – |
| Location on onset (% women–% men) | |||
| Podagra | – | M (52–57) | – |
| Ankle | – | – | – |
| Upper limb | – | M (44–47) | – |
| Fingers | – | – | – |
| Tophi | F* (27–10) | E | – |
| Monoarthritis | – | – | – |
| Polyarthritis | M* (56–80) | – | |
| Comorbidity (% women–% men) | |||
| Hypertension | F* (78–14) | – | – |
| Dyslipemia | – | – | – |
| Hypercholesterol. | – | – | – |
| Chr. heart disease | – | – | – |
| Peripheral arterial disease | – | – | – |
| Diabetes | E | – | – |
| Renal insufficiency | F* (54–11) | F*(30–12) | – |
Syn.tap diagnosed on a synovial tap, ACR diagnosed according to the ACR criteria of gout, Postmenopausal number of postmenopausal women, Duration the length of the period since first gout diagnosis, GP general practice, F more prevalent in female, M more prevalent in men, E equal between men and women
*p < 0.01 (significant); **p < 0.001 (significant)