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. 2010 Mar 23;38(8):2607–2616. doi: 10.1093/nar/gkq165

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Inter-GPS, slack and iterative refinement. Inter-GPS is shown in (A–B) and allows assembly graphs for different goal parts to share common intermediate parts reducing the assembly cost from 〈3, 8〉 to 〈3, 7〉 in A and 〈3, 6〉 in B. Slack is shown in (C–D) and allows suboptimal solutions to increase the potential for inter-GPS reducing the assembly cost from cost from 〈3, 7〉 in C to 〈3, 5〉 in D. Iterative refinement helps ensure common intermediate parts are constructed in the same way. For example, iterative refinement can turn the assembly graph in E into the assembly graph in B.