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Computational procedure of phosSNPs detection. In addition to ab initio prediction of kinase-specific phosphorylation sites using GPS 2.0 (22), we also detected potential phosSNPs by exact string matching with 23,978 experimentally identified human phosphorylation sites (Exp. Data) from a recent analysis (26). In total, there were 64,035 potential phosSNPs identified in 17,614 sequences.
