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. 2010 May 15;137(10):1601–1611. doi: 10.1242/dev.051219

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Fig. 7. — Inhibition of Fgf signals upregulates pSmad1/5/8 in olfactory placodal and sensory epithelial cells. (A) Cells in OP explants (n=6) express low levels of pSmad1/5/8 in the Msx1/2⁻ region and higher levels of pSmad1/5/8 in the Msx1/2⁺ domain. (B) In the presence of SU5402, cells in OP explants (n=6) co-express high levels of pSmad1/5/8 and Msx1/2. (C-F) In ovo Fgfr3c-ΔC-electroporation of stage 17 cultured to stage 21 (C,D) and stage 21 cultured to stage 27 (E,F) embryos (n=7) resulted in an upregulation of pSmad1/5/8 expression.