Figure 4.
BI-69A11 elicits more efficient cell death in UACC903 cells, compared with 29-1 cells. (A) 903 and 29-1 cells were exposed to different concentrations of BI-69A11 or UV light as a positive control and the percentage of cell death determined by trypan blue exclusion assay. (B) PARP cleavage was determined in 903 and 29-1 cells after treatment with BI-69A11 at 2, 4 and 6 h. Increased PARP cleavage is observed in 903 cells as compared to that observed in 29-1 cells after treatment with BI-69A11.