Figure 5. A2AR deficiency increases neutrophil p38 activity, and PSGL-1 clustering.
a, PSGL-1 distribution on neutrophil membranes. b, P-selectin and PSGL-1 on injured arteries. c and d, Western blot of P38 and phosphorylated p38 (pP38) of (c) spleen neutrophils and (d) carotid arteries 1 hour after injury (n = 3). e and f, Leukocyte rolling and adhesion through (e) P-selectin coated and (f) P-selectin and ICAM-1 coated micro-flow chambers (n=3).
