Figure 1.

Relative representation of DNA sequences assignable to homo sapiens chromosome 17 as a function of distribution over the chromosome, based on a 0.5-kb window. The green line shows distribution in 50 normal subjects, and the red line represents patients with relapsing MS. The blue horizontal line depicts the border of significance adopted for patients versus normal control subjects, which is equivalent to the mean + 4.6 SD (equals P = 0.01 after Bonferroni correction). The blue box indicates the genomic region linked to MS.⁴