Figure 2. Co-NPC-Tx: transplant histology.

Histological appearance (left 4x, insert 20x) of allogeneic islet/NPC co-transplantation in a representative Balb/c mouse 140 days after transplantation. Islets (Is) appeared embedded in tumor tissues, localized preferentially close to kidney tissue and stained strongly for insulin (brown). The frequency of leucocytes infiltrating the tumors and more specifically the islets, was very low (Insert B). However, when present, infiltrating cells were confined to the periphery of the islets whereas intra-islet infiltrating mononuclear cells were not observed (insert A, white arrow).