. Author manuscript; available in PMC: 2011 May 1.

Published in final edited form as: Semin Cell Dev Biol. 2010 Jan 4;21(3):269–275. doi: 10.1016/j.semcdb.2009.12.015

Table 1.

Summary of Dynein Binding Candidates, the Impact of Depletion/Disruption on Dynein Levels and Mitotic Progression.

Kinetochore Dynein Binding/Recruitment Partner	Molecular Interactions with Dynein	Impact on Kinetochore Dynein Levels	Mitotic Progression Phenotypes
Zw10	Dynein IC	reduced	Premature Anaphase Onset
Dynactin	Dynein IC	reduced	Prometaphase/Metaphase Arrest
NudE/EL	Dynein HC, IC, LC8	reduced	Metaphase Arrest
LIS-1	Dynein HC, IC	normal	Metaphase Arrest
NudC/CL	Dynein IC	NudC-N/A NudCL-reduced	Prometaphase/Metaphase Arrest
Spindly	N/A	reduced	Prometaphase/Metaphase Arrest