Table 1.
Expression level of L1 intracellular mutations
|
Mutation |
L1-1176 |
L1ΔRSLE |
L1-1180 |
L1-1147 |
L1-4A |
L1-1151Y>A |
|---|---|---|---|---|---|---|
| Percentage expression |
70 ± 12% |
68 ± 9% |
95 ± 12% |
57 ± 7% |
80 ± 12% |
95 ± 9% |
Mutant expression level is expressed as a percentage compared with L1KO neurons transfected with WT hL1. Neurite total expression is from neurites fixed and permeabilized and then stained with a monoclonal antibody that recognizes human L1 (7B5). All values are given as mean ± SEM.