Table 4.

Partial regression coefficients, hazard ratios with 95% confidence intervals, and P values of entry and instudy variables for incidence of coronary heart disease derived by multiple Cox’s regression analysis. Analysis was based on 174 cases of first myocardial infarction. Time dependent multiple Cox’s regression analysis used in analysis relating instudy variables to future coronary heart disease

Patient characteristic	Partial regression coefficient	Hazard ratio (95% CI)	P value
Entry variables:
Diastolic blood pressure	0.09	1.01 (0.92 to 1.11)	NS
Smoking*	0.41	1.52 (1.29 to 1.58)	<0.0001
Serum cholesterol concentration	0.32	1.18 (1.13 to 1.30)	<0.001
Target organ damage	0.78	2.11 (1.48 to 3.11)	<0.0001
Instudy variables:
Diastolic blood pressure	0.01	1.01 (0.90 to 1.21)	NS
Smoking*	0.03	1.03 (0.92 to 1.19)	NS
Serum cholesterol concentration	0.19	1.20 (1.08 to 1.32)	<0.001

NS=not significant.  

^*Relative number of smokers and non-smokers.