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. Author manuscript; available in PMC: 2010 Apr 28.
Published in final edited form as: Plant J. 2006 Apr;46(2):193–205. doi: 10.1111/j.1365-313X.2006.02680.x

Figure 4.

Figure 4

Alignment of Catharanthus roseus S-methyltransferase 1 (CrSMT1) with the crystallized caffeic acid O-methyltransferase (COMT) from Medicago sativa. Marked positions; residues and numbering from the M. sativa COMT (Zubieta et al., 2002): a, catalysis (transmethylation): W266, H269, D270, E297 and E330; b, SAM binding: D206–G212, D231, L232, D251–F253, K265 and W271; c, methyl acceptor binding: A162, A322, H323 and N324; d, binding of propanoid tail (e.g. of caffeic acid) in COMT: M130, M180, I316 and M320.