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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Biochem Pharmacol. 2010 Mar 16;80(1):72–79. doi: 10.1016/j.bcp.2010.03.010

Fig. 3.

Fig. 3

Accumulation and extrusion of Flutax-2 in tissues. (A) Flutax-2 accumulation in cell suspension of tissues. Cell suspensions of NCI/ADR-RES tumor, small intestine and liver of athymic mice were incubated with Flutax-2 (1 μM) in medium containing collagenase IV. The smear slides from each incubation condition were observed under microscope (left side, bright field; right side, fluorescence filed). (B) Accumulation and extrusion of Flutax-2 in cell suspensions of tumor, small intestine and liver. Increasing amounts of cell suspensions were incubated with Flutax-2 (1 μM) in medium containing collagenase. After 2 hr, cellular Flutax-2 was measured to evaluate accumulation (dashed line). The extrusion of the suspensions was measured after 2 hr additional incubation (solid line).