. Author manuscript; available in PMC: 2011 Jul 1.

Published in final edited form as: Biochem Pharmacol. 2010 Mar 16;80(1):72–79. doi: 10.1016/j.bcp.2010.03.010

Table 1.

Kinetics of Flutax-2 accumulation and efflux in NCI/ADR-RES cells and tumors.

	Accumulation		Extrusion		Efflux (extrusion/accumulation)
	K_{m-accumulation}	γ²	K_m-extrusion	γ²	Efflux (extrusion/accumulation)
Cells	2.49 ± 0.45 μM	0.999	1.31 ± 0.25 μM	0.996	0.526
Tumors	2.70 ± 1.03 μM	0.994	1.16 ± 0.25 μM	0.995	0.429

γ², correlation coefficient analyzed using nonlinear regression or sigmoid does-response with variable slope model. K_{m-accumulation} and K_m-extrusion, Michaelis-Menten constants of accumulation and extrusion.